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Pro-Female™ Hormone Cream

Availability: In stock

Regular Price: $29.99

Special Price $25.99

Quick Overview

Pro-Female™ Hormone Cream
ProbioticsWho may benefit from natural progesterone?
ProbioticsWomen with:   PMS Symptoms
ProbioticsMenopausal symptoms
ProbioticsOsteoporosis,  Help with concentration
ProbioticsAct as a natural diuretic,  Restore normal sleep pattern

  Product Description    More Information    Ingredients    Directions  


A bio-identical natural progesterone cream: 

Probiotics Formulated with 1000 mg of USP Micronized Standardized Progesterone per jar

Probiotics That is 84 mg. per 1/4 teaspoon dose

Probiotics For women of any age with PMS

Probiotics Per Menopause or Menopausal Symptoms

Probiotics Night Sweats, Hot Flashes, Low Libido, Trouble Sleeping  

Frequently Asked Questions

Highlights from the research of John R. Lee, M.D.

How does natural progesterone help?

During peri-menopause, many women do not ovulate regularly. After menopause, women do not ovulate at all. Without ovulation, the ovaries to do not produce progesterone. Progesterone levels get lower, night sweats, insomnia, changes in bleeding patterns, fatigue, depression and more. Adding progesterone may help restore the body’s balance and alleviate symptoms.

How soon can I see results?

Depending upon your individual body, your experience may not be the same as the next person’s. Some notice immediate results, while for others it takes longer for the progesterone to work with their symptoms. It may take up to 3 months to notice maximum benefits. Don’t give up! Since it is a natural substance, it may take longer for the body to respond than a power synthetic.

Is Progestin the same thing as progesterone?

No. Progesterone refers to the hormone produced in the body or from a plant source, but chemically identical to human progesterone. In contrast, Progestin is a synthetic progesterone that differs in structure to the body’s own progesterone. Natural progesterone is bio-identical.

IDo You Have Estrogen Dominance?

According to Dr. John Lee, the main causes of Estrogen Dominance are:

  • Nutritional imbalances
  • Effects of stress on the body
  • Use of birth control pills
  • Environmental toxins & synthetic chemicals, such as pesticides and plastics

These environmental toxins and chemicals affect the hormone balance of all living creatures including humans. They are called Xenohormones. Most of them have an estrogenic affect, which can cause hormonal imbalance. An excess or deficiency of estrogen has a strong effect on a woman’s body. Too much causes bloating, mood swings and insomnia. Too little causes lethargy, fatigue, depression and low libido.

Characteristics of Estrogen Dominance

Weight Gain, Insomnia, Fatigue, Memory Loss, Irritability, Acne, Cramping, Irregular Menstrual Flow, Depression, Panic Attacks, Osteoporosis, Cold Hands and Feet, Breast Tenderness, Hair Loss, Thyroid Imbalance, Increased Breast Cancer Risk, Fluid Retention (bloating) just to name some.

Note: Candida overgrowth causes estrogen dominance by using the body’s progesterone as food.  It devours progesterone, converting it into prednisone as its waste product.  When there is candida overgrowth, it consumes the progesterone, leaving excess estrogen to take up the receptors.

Use Pro-Biotics Plus and Oxy-Boost if you have signs of Candida.

Progesterone Use Can Help:

  • Utilize fat for energy
  • Restore normal sleep pattern
  • Restore proper cell oxygen levels
  • Help with concentration
  • Act as a natural anti-depressant
  • Act as a natural diuretic
  • Assist thyroid hormone action
  • Increase libido
  • Stimulate bone mineral density

* The statements made within this website have not been evaluated by the Food and Drug Administration. These statements and the products of this company are not intended to diagnose, treat, cure, or prevent any disease.

Can natural progesterone help with my hot flashes?


A study found that 83% of woman had a decrease in frequency and/or severity of their hot flashes while using natural progesterone. This was printed in Dr. Christiane Northrup’s book, The Wisdom of Menopause. Studies have also indicated that progesterone can eliminate up to 75% of all hot flashes in many woman.


Why do I have so much insomnia?


Insomnia in women over 40 is usually associated with the hormonal changes of per-menopause and menopause. Often there is too much estrogen relative to progesterone in the body. Remember estrogen is a central nervous system stimulant and progesterone has a calming effect on the brain. Some women experience excellent results when they rub ¼ tsp. on the back of their necks for their evening dose.


Can I use natural progesterone if I have Osteoporosis?


Dr. John Lee who studied the effect of progesterone on osteoporosis concluded that progesterone may help new bone by stimulating osteoblastic activity.


I have had a hysterectomy, but still have my ovaries. Should I still use natural progesterone?


According to Dr. Lee, this is a good choice. Following hysterectomy, the blood supply to the ovaries is significantly reduced and therefore so is their ability to produce progesterone. Within 2 years of the hysterectomy, production usually falls to postmenopausal levels.


Medical References

Anastasi J.N., Leonetti H. B., Wilson K.J. Topical progesterone crème has anti-proliferative effect on estrange-stimulated endometrium. Obstet & Gynecol. 2001. 94 (4 suppl.): 10S and Fertil Steril. 2004. 79 (1): 221-2

Bauliey E., CSchumacker M. Progesterone as a neuroactive neurosteroid, with special reference to the effect of progesterone on myelination. Steroids. 2000. Oct.-Nov.: 65 (10-11): 605-12.

Braverman, Eric. 1991. Natural estrogen and progesterone research indicates health benefits of natural vs. synthetic hormones. Total Health 13, no. 5 (October): 55.

Chang, K.J., et al. Influences of percutaneous administration of estradiol and progesterone on human breast epithelial cell in vivo. Fertility on Sterility 63: 785-91, 1995.

Cowan L.D., Gordis L., Tonascia J.A., et al. Breast cancer incidence in women with a history of progesterone deficiency. American Journal of Epidemiology. 1981: 114:209.

Dennerstein L., Spencer-Gardner C., Gotts G., Brown J.B., Smith M.A., Burrows G. D. Progesterone and the premenstrual syndrome: a double blind crossover trial. Br Med J (Clin Res Ed) 1985. Jun 1; 290 (6482): 1617-21.

History of progesterone as described by Goodman & Gilman. The Pharmacological Basis of Therapeutics. 6th edition, 1980: Chapter 61 (Estrogens and Progestins: 1420), 1085-1171.

Lee, D.R. M.D., 1990. Osteoporosis reversal: the role of progesterone. Intern Clin Nutr Rev 10: 384-91.

Lee, D.R. M.D., 1991. Is natural progesterone the missing link in osteoporosis prevention and treatment?.  Medical Hypotheses 35: 316-18.

Lee, D.R. M.D., 2003. Natural Hormones for Men: What Your Doctor May Not Tell You About Prostate Health and Natural Hormone Supplementation. Hormones Etc. p. 5-24.

Leonetti H.B., Longo S., Anasti J.N. Transdermal progesterone cream for vasomotor symptoms and postmenopausal bone loss. Obstet & Gynecol 1990. Aug; 94 (2): 225-8.


Micronized Progesterone; The progesterone used in this product is derived from the yam plant and is chemically identical to the human hormone, thus offering distinct advantages over synthetic progestins. 


Extract of Wild Yam;  Wild yam, Discorea villosa, is a tuberous vine native to North America. Wild yam has traditionally been used to treat menstrual and menopausal disorders. Wild yam shows mild estrogenic properties. The use of Mexican Wild Yam extract in recommended amounts is safe but it should be noted that pregnant women should avoid wild yam in its various forms.


Red Raspberry;  Red Raspberries contain strong antioxidants such as Vitamin C. Has a high ORAC level of 24 µmole/TE/g are similar to blueberries, well known for their antioxidant values.


Dandelion Root and Leaf;  When the body contains toxins, the detoxification effects of the dandelion can yield clear skin. Dandelions are also high in vitamin A, known for its complexion benefits. Dandelions also work as a natural diuretic, ridding the body of excess fluids and toxins.


Aloe Vera;  Has antibacterial, antifungal and antiviral compounds.. It also has immune-stimulating and anti inflammatory compounds, and it stimulates collagen synthesis and skin regeneration. Aloe gel contains vitamins C and E, plus the mineral zinc.


Essential Oils;  Essential oils are absorbed in minute quantities through the skin.  Used to help the cream penetrate and helps replenish the skin.


Lecithin;  Used as a as a natural emulsifier, makes the cream; creamy and thick.


Isopraffin;  Used as an emollient, and a thickening agent.


Chamomile Extract; Chamomile Extract contains active Flavonoid and Essential Oil compounds, which are particularly advantageous in the care of sensitive skin. Anti-free radical action and inhibition of the super oxide radical synthesis.


Rosemary Extract; Anti-oxidizing powers, may help support, increase circulation and increase collagen which will increase skin's elasticity.


Rheocare; Used for a thickening agent. Uniphen; Used as a preservative.  And Purified Water; As Purified Water.


Micronized Progesterone, Extracts of Wild Yam, Red Raspberry, Dandelion Root And Leaf, Aloe Vera, Essential Oils, Lecithin, Isopraffin, Chamomile Extract, Rosemary Extract, Rheocare, Uniphen, Purified Water.

Directions are as follows:


Massage 1/8-1/4 tsp. into your skin twice daily. Apply to inner arms, wrist, and palms of hands, thighs, face, or neck. These areas are most absorbable and the progesterone absorbs through the skin in one to two minutes.


Each jar contains 2 ounces of cream. At ¼ teaspoon per dose, the jar contains 48 doses.


Menstruating Women


The first day of bleeding or menses is Day 1. Start the crème on Day 12 and continue through Day 26.


Irregular Cycles


If you have just had a cycle, use the crème from Day 12-26 of your cycle. Then stop. If your period does not come within a week, consider the last day you took the progesterone as Day 1 of a new cycle. Then begin on Day 12 again.  If periods stop for 3 consecutive months, begin to use the crème for 25 days of each month.


Non-Menstruating Women 


Use the cream for 25 days per month. Take 2-5 days off to allow receptor sites to remain active.

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